Научно-практический журнал
[About us] Journal 'Cytokines & Inflammation'

197376, Санкт-Петербург, ул. Акад. Павлова, д. 12,
Институт экспериментальной медицины РАМН
Тел.: (812) 543 52 14, +7 921 984 11 30, +7 921 909 55 49
Факс: (812) 543 52 14
E-mail:
Web: www.cytokines.ru


  


Year 2018
1-4 issues

About journal

Current year
Archive

Columns
Subscription

Rules for authors

Contact us

Search

Site map

Our partners:
Русский языкEnglish language
Site map Contact us

Contents | Next article | Previous article

Journal 'Cytokines & inflammation', 2008, No. 1

Subscribe for 2019 year

Order this issue

Order PDF of this article

Reviews

Number 1'2008

INFLUENCE OF MYELOPEPTIDES ON LYMPHOCYTE PROLIFERATION AND PRODUCTION OF IL?1? AND TNF? BY MONONUCLEAR CELLS, MONOCYTES AND NEUTROPHILS

S.V. Gein, T.V. Gavrilova, V.A. Chereshnev, M.V. Chereshneva

It was established that myelopeptides MP-1, MP-3, MP-5 and MP-6 decreased proliferative activity of peripheral blood lymphocytes and IL?1? production by mononuclear cells. MP-5 depressed IL?1? and TNF? synthesis. Depression of proliferation and IL?1? production took place only in stimulated cultures and in cell to cell cooperation conditions. Effects of myelopeptides on proliferative response in lymphocyte fraction and on production of proinflammatory cytokines by purified monocytes and neutrophils were not observed. (Cytokines and Inflammation. 2008. Vol. 7, No. 1. P. 24-28.)

Keywords: myelopeptides, monocytes, neutrophils, proliferation, cytokines.

Contents | Next article | Previous article


© 2007-2019 Cytokines and inflammation