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Journal 'Cytokines & inflammation', 2012, No. 2

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Original Articles

Number 2'2012

Comparative characteristics of antibacterial properties of synthetics peptides of the GM-CSF active site and factors of the supernatants of CD34+45 dim cells precursors of hemopoesis

V.A. Zurochka,A.V. Zurochka,E.G. Kostolomova, M.A. Dobrynina,Yu.G. Sukhovey,V.A. Gritsenko, A.A. Kolobov, A.S. Simbirtsev

Antibacterial activity of the GM-CSF active site synthetic peptides and supernatants of CD34+45 dim hematopoietic progenitor cells were studied. It was found that GM-CSF peptides and cell supernatants have strong antibacterial activity, and the combination of these substances has a higher activity than the individual substances. Possible mechanisms of the effects of synthetic peptides and factors of CD34+45dim supernatants are discussed. (Cytokines and Inflammation. 2012. 2012. Vol. 11. № 2. P. .)

Keywords: GM-CSF peptides.

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