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Journal 'Cytokines & inflammation', 2012, No. 2

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Original Articles

Number 2'2012

Th1/Th2 cytokine profile production in patients with different clinical variants of autoimmune diabetes mellitus

T.V. Saprina, F.E. Lazarenko, T.S. Prokhorenko, N.V. Ryazantseva, I.N. Vorozhtsova

In patients with latent autoimmune diabetes, the loss of functional parenchyma and manifestation of insulin deficiency develops slowly, stretching out for years, due to the nature of their cytokine-mediated cellular interactions. This requires a more active and thorough diagnostic tactics using immunological methods of examination in patients of older age group, where diabetes is represented by various pathogenic variants. (Cytokines and Inflammation. 2012. Vol. 11. № 2. P. 51–57.)

Keywords: latent autoimmune diabetes mellitus, diabetes mellitus type 1, cytokines, immunopathogenesis.

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