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Journal 'Cytokines & inflammation', 2014, No. 4

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Number 4'2014

The role of the local inflammation in the ovulation and implantation

V.I. Shcherbakov, T.I. Ryabichenko, G.A. Skosyreva, A.N. Trunov

Analytical review investigates the data on physiological processes such as ovulation and implantation, which are considered from the standpoint of the inflammatory response. Data are presented showing that a local inflammatory reaction has a constructive role in these important reproductive events. They not only expand the boundaries of understanding the role of inflammation as a pathological process, but also form an entirely new concept of physiological inflammation. This has not only theoretical but also practical interest, since the widespread use of anti-inflammatory drugs of different classes in clinical practice can lead, through the blockade of the local inflammatory reaction, to the infertility. (Cytokines and Inflammation. 2014. Vol. 13. № 4. P. 16–22.)

Keywords: local inflammation, cytokines, endometrium, ovaries, ovulaition.

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