Научно-практический журнал
[About us] Journal 'Cytokines & Inflammation'

197376, Санкт-Петербург, ул. Акад. Павлова, д. 12,
Институт экспериментальной медицины РАМН
Тел.: (812) 543 52 14, +7 921 984 11 30, +7 921 909 55 49
Факс: (812) 543 52 14
E-mail:
Web: www.cytokines.ru


  


Year 2018
1-4 issues

About journal

Current year
Archive

Columns
Subscription

Rules for authors

Contact us

Search

Site map

Our partners:
Русский языкEnglish language
Site map Contact us

Contents | Next article | Previous article

Journal 'Cytokines & inflammation', 2017, No. 1

Subscribe for 2019 year

Order this issue

Order PDF of this article

Original Articles

Number 1'2017

Cytokine profile of regulatory T cells in patients with chronic urticaria

N.I. Baranova, S.V. Kozhenkova, M.V. Osipova

The aim of the study was a comparative analysis of the regulatory T cells function in patients with chronic autoimmune urticaria (CAU) and chronic idiopathic urticaria (CIU). We analyzed the functions of natural regulatory T cells (Treg) on the basis of expression FOXP3 mRNA, adaptive populations: Tr1 by production of IL-10, Th3 – by TGFβ, and Th17 by IL-17A; differentiation antigens CD3, CD4, CD16, CD19. There were no significant differences in the natural regulatory T cells by the expression of FOXP3 mRNA in patients with CAU and CIU and healthy individuals. Adaptive regulatory populations Tr1, Th3, and Th17 demonstrated both common features of functioning in patients with CAU and CIU and the special ones characteristic of each form of chronic urticaria. The data obtained can be used as diagnostic criteria for two forms of chronic urticaria. (Cytokines and Inflammation, 2017. Vol. 16. № 1–2. P. 37–41.)

Keywords: chronic autoimmune urticaria, chronic idiopathic urticaria, regulatory T cells, cytokines.

Contents | Next article | Previous article


© 2007-2019 Cytokines and inflammation