Научно-практический журнал
[About us] Journal 'Cytokines & Inflammation'

197376, Санкт-Петербург, ул. Акад. Павлова, д. 12,
Институт экспериментальной медицины РАМН
Тел.: (812) 543 52 14, +7 921 984 11 30, +7 921 909 55 49
Факс: (812) 543 52 14
E-mail:
Web: cytokines.ru


  


Year 2017
Number 3

About journal

Current year
Archive

Columns
Subscription

Rules for authors

Contact us

Search

Site map

Our partners:

https://pornoseksxxx.com/

Русский языкEnglish language
Site map Contact us

Contents | Next article | Previous article

Journal 'Cytokines & inflammation', 2002, No. 3

Subscribe for 2018 year

Order PDF of this article

Original Articles

Number 3'2002

CYTOKINES' LEVEL IN ORAL CAVITY SECRETIONS OF ASTHMATIC CHILDREN

M.A. Abajidi, E.F. Lukushkina, I.V. Mayanskaya, N.I. Tolkachova, V.I. Ashkinazi

In bronchial asthma children significant growth of IL-1b, TNFa and IL-4 levels in saliva were revealed, the average data were 8,9 (IL-1b), 2,6 (TNFa) and 1,8 (IL-4) times higher than in group of healthy children. The highest levels (average meanings as well as percent distribution of cases with high levels) were found in children with severe course of the disease. Variation coefficient for all cytokines in asthmatics was higher than that in controls, especially in patients with severe course of the disease (IL-1b " TNFa " IL-4). Clinical remission was accompanied by significant decrease of IL-4, but the levels reached those of the control group only in patients with moderate and mild asthma course. The changes of IL-1b and TNFa levels were insignificant, and were revealed only in patients with severe asthma course. No correlation was found between the cytokines' levels in serum and saliva, the levels of all three cytokines in saliva in most of cases were higher than those in serum, especially for IL-1b in patients with severe asthma course. Possible sources of cytokines in saliva and their possible role as biological markers are discussed.

Contents | Next article | Previous article


© 2007-2018 Cytokines and inflammation