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Journal 'Cytokines & inflammation', 2003, No. 4

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Number 4'2003

CYTOKINES AND MEDIATOR FUNCTIONS OF UROEPITHELIAL CELLS IN INFLAMMATORY REACTIONS OF URINARY TRACT

A.N. Mayansky

The interactions between uroepithelial cells and Escherichia coli are reviewed as related to the contact (adhesive) bacterial pathogenicity in mucosal infections. The epithelium-targeted pyogenicity of uropathogenic Escherichia coli associated with the inducible production of inflammatory cytokines is presented as an alternative to the invasive and cytodestructive strategy of bacteria. (Cytokines and Inflammation, 2003, Vol. 2, № 4, p. 3-9)

Keywords: epithelium, infection, cytokines.

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