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Journal 'Cytokines & inflammation', 2006, No. 1
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Original Articles
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Number 1'2006
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NEUTROPHIL-DEPENDENT INFLAMMATION UNDER INTRAVENOUS HOMEOSTASIS DESTABILIZATION
M.I. Zaslavskaia, A.N. Mayanskii
The functional resources of blood and peritoneal exudation rat neutrophils were investigated under zymozan-induced intravascular homeostasis destabilization. Suppression of neutrophil migration into the site of peritoneal inflammation within 1 hour after intravascular injection of zymozan was detected. The mobilization blockade of neutrophils did not depend on the type of abdominal irritant and the site of inflammation. The temporary neutrophil mobilization blockade did not a result of circulating blood cell decrease, and also was not accompanied by change in the ability to spontaneous migration, specific (C3b-, IgG-dependent) and nonspecific adhesion. (Cytokines and Inflammation. 2006. Vol. 5, N 1. P. 50-52.)
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