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Journal 'Cytokines & inflammation', 2007, No. 2

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Original Articles

Number 2'2007

CLINICAL AND IMMUNOLOGICAL FEATURES OF SEPSIS AND TNFα AND IL-10 GENE POLYMORPHISMS IN PATIENTS WITH SURGICAL INFECTION

E.V. Kurganova, О.V. Golovanova, А.V. Shevchenko, I.G. Rakova, E.I. Streltzova, А.А. Ostanin, E.R. Chernykh, V.I. Konenkov

The distribution of alleles and genotypes frequency of the TNFα and IL-10 genes was studied in 61 patients with surgical sepsis and in 52 healthy individuals. Our results show that generalization of surgical infection is characterized by increased frequency of mutant A allele of TNFα (-308 G

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